Aspirin Use significantly linked to AKI Risk in Critical Chest Trauma Patients: Study
Researchers have found a significant association between aspirin use and an increased risk of acute kidney injury (AKI) in critically ill patients with chest trauma in a new study.
Non-steroidal anti-inflammatory drugs (NSAIDs) are increasingly utilized in trauma patients, particularly those with critical chest trauma who are susceptible to significant blood loss, leading to renal hypoperfusion.
Acute kidney injury (AKI) is known to carry a poor prognosis in chest trauma patients. Therefore, investigating the potential association between NSAID use and acute kidney injury risk in critical patients with chest trauma is crucial. They selected patients admitted to the intensive care unit (ICU) with chest trauma from the Medical Information Mart for Intensive Care III (MIMIC-III) dataset (2001–2012) and the Medical Information Mart for Intensive Care IV (MIMIC-IV) dataset (2013–2019). Propensity score matching (PSM) was used to match patients receiving NSAIDs with those not receiving treatment. Logistic regression was employed to assess the association between different types of NSAIDs and acute kidney injury in these patients.
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