Gout under reported finding in patients of peritoneal and hemodialysis
North America: A new study found that gout occurs frequently and is often underreported in patients undergoing hemo and peritoneal dialysis. The study results were published in the journal Kidney360.
An increased frequency of Gout in renal disease patients causes a significant burden on quality of life. There is huge uncertainty regarding the prevalence of gout, and its association with outcomes in hemodialysis (HD) and peritoneal dialysis (PD) populations in North America. Hence researchers conducted a study to understand the same.
The study was carried out using data from North American cohorts of 70,297 HD patients (DOPPS, 2012-2020) and 5117 PD patients (PDOPPS, 2014-2020). Participants were considered to have gout if they had an active prescription for colchicine or febuxostat; or an active prescription for colchicine, febuxostat, or allopurinol; or had an active prescription for colchicine, febuxostat, or allopurinol, or prior diagnosis of gout. A comparison of outcomes among patients with or without gout was done using propensity score matching. Outcomes included erythropoietin resistance index (ERI=erythropoiesis stimulating agent dose per week/(hemoglobin×weight)), all-cause mortality, hospitalization, and patient-reported outcomes (PROs).
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