Long-Term Ozone Exposure Linked to Increased Risk of Chronic Kidney Disease Mortality, reveals study
Chronic kidney disease (CKD) is a significant public health concern worldwide, with mortality rates continuing to rise. While the adverse effects of environmental pollutants on respiratory and cardiovascular health are well-documented, the impact on renal outcomes remains unclear.
Ozone, a major component of air pollution, is known to induce oxidative stress and inflammation, which may contribute to the progression of CKD. A recent study aimed to investigate the association between long-term ozone (O3) exposure and mortality in individuals with CKD. This study was published in the journal of BMC Nephrology by Ejin Kim and colleagues.
A cohort of 61,073 participants was included in this study, with researchers employing Cox proportional hazards models to analyze the association between ozone exposure and the risk of end-stage renal disease (ESRD) and mortality. Ozone concentrations were calculated based on exposure one year before enrollment using inverse distance weighting (IDW) for interpolation. Models were adjusted for socioeconomic status and other measured pollutants.
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