Timely management of psoriasis lowers infection and mortality risk in ESRD: Study
Psoriasis is a chronic inflammatory skin disease related to T-cell-mediated immunity. The global prevalence of psoriasis is 0.91–8.5%. Despite novel treatments, psoriasis is associated with a considerable socioeconomic burden and with a variety of comorbidities, which reduce the quality of life of psoriatic patients.
It is a serious and refractory disease due to "invisible inflammation". Psoriasis is not limited to the skin; the "psoriatic march" leads to elevated levels of oxidative stress, endothelial dysfunction, abnormal glucose metabolism, insulin resistance, and ultimately cardiovascular disease. Several studies have evaluated the relationship between psoriasis and metabolic, kidney or cardiovascular disease, but none have addressed the relationships between the subtype of, or treatment for, psoriasis and chronic kidney diseases such as end-stage renal disease (ESRD).
Recent study results suggest that psoriasis in end-stage renal disease patients may have an increased risk of infection and treatment of psoriasis is associated with a reduced risk of some infections and improved survival. The findings have been put forth in American Journal of Medical Sciences.
Psoriasis impairs the quality of life of approximately 7.5 million Americans and is associated with serious comorbidities. Because of chronic vascular access and epidermal dysfunction, end-stage renal disease (ESRD) patients with psoriasis may be at greater risk for infection, and psoriasis treatment could affect this risk.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.