Hereditary angioedema medicine: Takeda Biopharma launches CINRYZE in India

Hereditary Angioedema (HAE) is a rare genetic condition that causes swelling in different parts of the body like limbs, face, abdomen, and larynx .;

Published On 2022-12-14 06:36 GMT | Update On 2022-12-14 06:42 GMT

New Delhi: Takeda Biopharmaceuticals India Private Limited (formerly known as Baxalta Bioscience India Pvt. Ltd.), a global values-based, R&D-driven biopharmaceutical company has launched CINRYZE an injectable prescription medicine for the treatment of hereditary angioedema (HAE) patients.

With eight years of global clinical experience proving efficacy and safety, CINRYZE has the potential to mark a breakthrough in the episodic treatment, short and long-term prophylaxis for HAE. Moreover, CINRYZE is the pioneer C1 esterase inhibitor (C1-I NH) approved by the FDA & EMA for the symptomatic management of HAE and for preventing future angioedema attacks.

CINRYZE is indicated in India for:

a. Routine prevention (prophylaxis) of angioedema attacks in adults, adolescents and children 6 years of age and above with HAE.

b. Treatment of angioedema attacks and pre-procedure prevention of angioedema attacks in adults, adolescents and children 2 years of age and above with HAE.

Speaking at the launch, Serina Fischer, General Manager, Takeda Biopharmaceuticals India Private Limited said, "At Takeda, we are committed to bringing innovative treatment to fulfil the unmet medical needs across our core therapy areas. We are confident that the launch of Cinryze will bridge the gap in the treatment of HAE patients in India. The launch furthers our commitment towards rare diseases patients in India."

Sony Paul, Franchise Head, Rare Diseases, Takeda Biopharmaceuticals India Private Limited added, "As per data, there are likely to be more than 30,000 undiagnosed patients at present in the country. These patients are suffering due to the lack of diagnosis and treatment. With the launch of Cinryze, our aim is to treat acute attacks of HAE and prevent future HAE attacks by prophylactic regime improving the quality of life of HAE patients."

Hereditary Angioedema (HAE) is a rare genetic condition that causes swelling in different parts of the body like limbs, face, abdomen, and larynx .

HAE is caused by a mutation in the gene which produce protein called the C1 esterase inhibitor leading to its reduced level or compromised functioning. Symptoms of HAE often present in childhood, and while attacks can occur at any age, early onset may predict a more severe disease course. Attacks often occur in children without a clear trigger, and may affect a child's participation in school, activities, and sports, which can leave them feeling socially isolated.

It can be life-threatening in severe cases in which the swelling attacks can manifest in the larynx (voice box), or trachea (windpipe).

The disease is usually identified by recurrent episodes of fluid accumulation outside the blood vessels, causing rapid swelling of body tissues. The symptoms of HAE could be like an allergic reaction; however, the potential outcome could be life-threatening in case of HAE. Due to the lack of awareness among healthcare professionals, HAE is highly underdiagnosed in the country.

Takeda Biopharmaceuticals India Private Limited (formerly known as Baxalta Bioscience India Private Limited) is a part of Takeda Pharmaceutical Company Limited's group of companies headquartered in Japan.

Read also: Takeda to acquire Oral Allosteric TYK2 Inhibitor NDI-034858 from Nimbus Therapeutics

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Ruchika Sharma

Ruchika Sharma joined Medical Dialogue as an Correspondent for the Business Section in 2019. She covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She has completed her B.Com from Delhi University and then pursued postgraduation in M.Com. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751

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Hereditary angioedema medicine: Takeda Biopharma launches CINRYZE in India

Hereditary Angioedema (HAE) is a rare genetic condition that causes swelling in different parts of the body like limbs, face, abdomen, and larynx .;

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