JnJ discontinues mid stage study of skin disease drug
Written By : Ruchika Sharma
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2025-12-27 10:00 GMT | Update On 2025-12-27 11:12 GMT
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Spring House: Johnson & Johnson has discontinued a mid-stage trial of its experimental drug for moderate to severe atopic dermatitis after the treatment failed to deliver efficacy goals in an interim analysis.
The Phase 2b DUPLEX-AD proof-of-concept study (95475939ADM2001) evaluated JNJ-95475939 (JNJ-5939) for the treatment of moderate to severe atopic dermatitis.
The results of a planned interim analysis met pre specified criteria for early termination of the study, as they did not meet the high-bar efficacy required for advancing clinical development programs for atopic dermatitis.
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