Secured nearly half of Pfizer 2021 global output of COVID-19 shots, says EU

"We now have agreed with BioNTech and Pfizer to extend this contract. With the new agreement we could purchase a total of up to an additional 300 million doses of the BioNTech vaccine," Ursula von der Leyen told a news conference on Friday.

Pfizer was more cautious.

"We are in talks with the European Commission about an amendment to our existing supply agreement for Comirnaty, the Pfizer-BioNTech COVID-19 vaccine," it said in a statement.

The move would allow EU governments to double their orders from Pfizer to 600 million doses, von der Leyen said, as the 27-nation bloc races to ramp up the vaccination of its 450 million people. Each recipient of the Pfizer vaccine need two doses to develop maximum protection.

In a separate announcement, the EU drug regulator changed its recommendation for the use of the Pfizer vaccine, allowing the extraction of six doses from a vial instead of five, confirming an earlier Reuters story.

That would increase available doses by 20%. The pricing would continue to be calculated in doses and not in vials, a spokesman for Pfizer said, meaning that there would be no discount on prices paid by the EU for new deliveries. An EU document seen by Reuters in December showed the price was 15.5 euros ($19) per dose.

Von der Leyen said 75 million of the additional doses under the new deal would be delivered in the second quarter of this year, and the rest by the end of 2021. Pfizer said that in total 500 million doses would be available to the EU by the end of this year, and an option for another 100 million could be taken up.

Production capacity

The large EU order is likely to require an expansion of Pfizer-BioNTech production capacity this year, as the companies already have deals with other wealthy nations for large supplies in 2021.