Sinovac COVID vaccine CoronaVac shows positive results in early trial
The phase II clinical trial results show that the vaccine induces neutralizing antibodies 14 days after the vaccination with a 0,14 day schedule.;
Beijing: Sinovac Biotech Ltd. has announced positive preliminary results of phase I/II clinical trial for the Company's COVID-19 vaccine candidate, named CoronaVac, which showed favorable immunogenicity and safety profiles.
The phase I/II clinical trials were designed as randomized, double-blind and placebo-controlled studies. In total, 743 healthy volunteers, aged from 18 to 59 years old, enrolled in the trials. Of those, 143 volunteers are in phase I and 600 volunteers are in phase II. There have been no severe adverse event reported in either the phase I or phase II trials. The phase II clinical trial results show that the vaccine induces neutralizing antibodies 14 days after the vaccination with a 0,14 day schedule. The neutralizing antibody seroconversion rate is above 90%, which concludes the vaccine candidate can induce a positive immune response.
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