Furosemide accelerates postpartum BP recovery in women with HDP: Study
Philadelphia: A short-course of furosemide after childbirth may significantly improve BP control in women with hypertensive disorders of pregnancy (HDP), specifically in women without severe disease.
Persistent postpartum hypertension is a significant cause of morbidity in mothers. Joana Lopes Perdigao, University of Pennsylvania, University of Pennsylvania Perelman School of Medicine, Philadelphia, and colleagues aimed to study the effect of furosemide on postpartum blood pressure recovery in women with HDP.
For the purpose, the researchers performed a randomized, double-blind, placebo-controlled trial. The trial was of a 5-day course of 20 mg oral furosemide versus placebo in women with gestational hypertension and preeclampsia with/without severe features from June 2018 to October 2019.
Primary outcomes were persistent hypertension at 7 days postpartum and days to resolution of hypertension, stratified by severe/nonsevere hypertensive disease. Secondary outcomes included readmissions and need for additional hypertensive medication.
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