Sleep duration and depression independently linked to risk of cardiometabolic diseases

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-10-16T19:30:40+05:30 | Updated On 16 Oct 2022 7:30 PM IST

In a new study conducted by Xunjie Cheng and team it was found that short or extended sleep durations and depression were both independently linked to an elevated risk of Cardiometabolic diseases (CMDs) and death. The findings of this study were published in Atherosclerosis Journal.

It is uncertain if depression and sleep duration are separate or overlapping risk factors for CMDs and mortality because these two variables were only seldom mutually adjusted in studies. In order to assess the separate and combined relationships between depression and sleep duration and CMDs and mortality, researchers conducted this study.

261,297 patients who did not have diabetes mellitus (DM), hypertension, a stroke, or any of the other conditions listed above at the beginning of the study were included. Three categories of sleep duration (short: 7 h/day, referent: ages 39–64: 7-9 h/day; ages 65+: 7-8 h/day, and long: ages 39–64: >9 h/day; ages 65+: >8 h/day) were used. All-cause mortality, cardiovascular mortality, hypertension, stroke, coronary heart disease (CHD), and diabetes mellitus were the major outcomes.

The key findings of this study were:

1. Except for the relationship between short sleep duration and stroke (HR, 1.03; 95% confidence interval [CI], 0.97-1.10), depression and short or long sleep duration were independently associated with an increased risk of CMDs and mortality among the 261,297 participants (hazard ratio [HR], 1.10–1.38).

2. Short sleep duration and depression have been shown to have significant additive interactions with regard to all-cause mortality (RERI, 0.19; 95% CI, 0.02-0.37) and coronary heart disease (CHD, 0.30; 95% CI, 0.11-0.48).

In conclusion, it is clear from the findings of this study that in respect to all-cause mortality and CHD, researchers found substantial additive interactions between depression and short sleep duration.

Reference:

Cheng, X., Ouyang, F., Ma, T., He, L., Gong, L., Yin, J., Zhang, G., & Bai, Y. (2022). The individual and joint associations of depression and sleep duration with cardiometabolic diseases and mortality: A prospective cohort study. In Atherosclerosis. Elsevier BV. https://doi.org/10.1016/j.atherosclerosis.2022.09.016

cardiometabolic diseasedepressionSleep durationAtherosclerosis journal

Source : Atherosclerosis

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751