Probiotics decreases atopic dermatitis risk in infants having family history: Study

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2020-12-21T17:30:56+05:30 | Updated On 22 Dec 2020 2:50 PM IST

China: Probiotics are beneficial for reducing the risk of atopic dermatitis (AD) in infants with a family history of the condition, finds a recent study published in the journal Archives of Medical Science.

The study by Jia-huan He, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China, and colleagues aimed to investigate the preventive effects of probiotics' oral administration on the severity and incidence of atopic dermatitis in infants.

The study included a total of 396 full-term infants. They were assigned to two groups; 132 newborns without a family history of AD were included in Group A and other 264 newborns were randomly divided into groups B and C. Those in group A and B were only breastfed while those in group C were administered probiotics in addition to breastfeeding.The information of all subjects was recorded, and the incidence of AD was followed up. The levels of serum IgE and IL-4 were measured at the age of 3 years.

Key findings of the study include:

The incidence of AD in infants in group B was higher than that in group A at 3 months, 4–6 months, and 7–36 months after birth, together with increased symptom scores.
For infants in group C, the incidence of AD at 4–6 months and 7–36 months after birth and the SCORAD scores at 0–3 months and 4–6 months after birth were lower than those in group B.
The levels of IgE and IL-4 in group B were higher than those in groups A and C at 36 months old.

"Probiotics addition could favor the establishment of the intestinal microecological balance in the neonatal period, thereby reducing the incidence of AD, decreasing the levels of serum immune indexes and alleviating the severity of the disease," wrote the authors.

"Clinical study on prevention of atopic dermatitis by oral administration of probiotics in infants," is published in the journal Archives of Medical Science.

DOI: https://www.archivesofmedicalscience.com/Clinical-study-on-prevention-of-atopic-dermatitis-by-oral-administration-of-probiotics,127658,0,2.html

Archives of Medical Scienceatopic dermatitisprobioticsinfants

Source : Archives of Medical Science

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751