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Bariatric surgery prevents cancer in patients with diabetes and obesity: Study
Sweden: A recent study in the journal Diabetes Care reports that in patients with obesity and diabetes, bariatric surgery prevents cancer. Also, durable diabetes remission was shown to be associated with reduced cancer risk.
Type 2 diabetes and obesity are related to serious adverse health effects, including cancer. Although bariatric surgery has been shown to lessen cancer risk in obese patients, the effect of bariatric surgery on cancer risk in patients with diabetes and obesity is not much studied. Kajsa Sjöholm, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden, and colleagues examined the long-term incidence of cancer after bariatric surgery and usual care in patients with obesity and diabetes in the matched prospective Swedish Obese Subjects (SOS) study.
The SOS study examines long-term outcomes after bariatric surgery or usual care. This analysis included 701 patients with obesity and type 2 diabetes at baseline, 393 underwent bariatric surgery and 308 received conventional obesity treatment. Using the Swedish National Cancer Register, information on cancer events was obtained. The Median follow-up time was 21.3 years.
Based on the study, the researchers found the following:
- During follow-up, the incidence rate for first-time cancer was 9.1 per 1,000 person-years in patients with obesity and diabetes treated with bariatric surgery and 14.1 per 1,000 person-years in patients treated with usual obesity care (adjusted hazard ratio 0.63).
- Surgery was associated with reduced cancer incidence in women (0.58), although the sex-treatment interaction was nonsignificant.
- Diabetes remission at the 10-year follow-up was associated with reduced cancer incidence (0.40).
The researchers concluded, "these results suggest that bariatric surgery prevents cancer in patients with obesity and diabetes and that durable diabetes remission is associated with reduced cancer risk."
Reference:
Association of Bariatric Surgery With Cancer Incidence in Patients With Obesity and Diabetes: Long-Term Results From the Swedish Obese Subjects Study. Kajsa Sjöholm, Lena M.S. Carlsson, Per-Arne Svensson, Johanna C. Andersson-Assarsson, Felipe Kristensson, Peter Jacobson, Markku Peltonen, Magdalena Taube. Diabetes Care Nov 2021, dc211335; DOI: 10.2337/dc21-1335
MSc. Biotechnology
Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at  editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751