Diabetes associated with high prevalence of sarcopenia, study finds

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-01-01T10:45:32+05:30 | Updated On 1 Jan 2022 12:00 PM IST

China: A recent study in the Journal of Clinical Endocrinology & Metabolism has suggested that sarcopenia is more common in diabetes patients. The probable risk factors include age, HbA1c, diabetic nephropathy, visceral fat area (VFA), duration of diabetes, and HS-CRP.

Sarcopenia is the loss of muscle mass related specifically to aging. It affects your balance, gait, and overall ability to perform daily tasks. Previous studies have shown sarcopenia prevalence in diabetes patients to be three times higher than in non-diabetic patients and are related to poor prognosis. Bin Ma, Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, P.R.China, and colleagues aimed to investigate the global pooled prevalence and risk factors of sarcopenia in diabetes patients.

For this purpose, the researchers identified relevant studies published until November 30, 2020, from online databases. The study included participants with age ≥18 years with clinically diagnosed diabetes. Sex and diabetes type were not restricted. Two reviewers independently extracted the data using a standard collection form.

Key findings include:

The pooled prevalence of sarcopenia in patients with diabetes was 18%; subgroup analysis showed that sarcopenia was more prevalent in males than in females, as well as being more prevalent in Asia than in South America and Oceania.
Age (OR, 1.10), HbA1c (OR, 1.16), visceral fat area (VFA) (OR, 1.03), diabetic nephropathy (OR, 2.54), duration of diabetes (OR, 1.06), and HS-CRP (OR, 1.33) were risk factors for sarcopenia in patients with diabetes.

Based on the findings the researchers concluded that in the future, medical staff should not only pay attention to the early screening of sarcopenia in high-risk groups but also provide information on its prevention.

Reference:

Liyuan Feng, Qianqian Gao, Kaiyan Hu, Mei Wu, Zhe Wang, Fei Chen, Fan Mei, Li Zhao, Bin Ma, Prevalence and risk factors of sarcopenia in patients with diabetes: A meta-analysis, The Journal of Clinical Endocrinology & Metabolism, 2021;, dgab884, https://doi.org/10.1210/clinem/dgab884

Source : Journal of Clinical Endocrinology & Metabolism

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751