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Longer the duration of diabetes, higher is risk of heart failure
China: Research published in The Journal of Clinical Endocrinology & Metabolism has mentioned that the duration of diabetes history plays a crucial role in determining the risk of heart failure.
The data needs to be more transparent on the interplay between the duration of diabetes and the risk of heart failure.
A team of researchers investigated this association in a study of 23 754 individuals who had a history of diabetes without Heart Failure (HF) during the baseline recruitment of UK Biobank. Duration of diabetes was self-reported, and HbA1c levels reflected glycemic control.
The study results include the following:
- There was a positive association between diabetes duration and HbA1c levels with heart failure risk.
- The hazard ratios for diabetes durations of 5 to less than 10, 10 to less than 15, and 15 years or more were 1.09, 1.13 and 1.32, respectively, with HR for HbA1c of 53.0 to less than 58.5 mmol/mol, 58.5 to less than 63.9 mmol/mol and 63.9 mmol/mol or greater were 1.15, 1.07 and 1.46 respectively.
- Those with the most prolonged disease duration of more than or equal to 15 years and poorer glycemic control had a significantly higher risk of Heart failure.
The conclusion states that those with a longer duration of diabetes and increasing HbA1c levels have a higher risk of heart failure.
This is an important finding leading to the possible prevention of heart failure in diabetic patients with consideration in clinical practices and policy-making.
Further reading:
Huan-Huan Yang et al. Duration of Diabetes, Glycemic Control, and Risk of Heart Failure Among Adults With Diabetes: A Cohort Study, The Journal of Clinical Endocrinology & Metabolism, 2022; dgac642, https://doi.org/10.1210/clinem/dgac642
BDS, MDS in Periodontics and Implantology
Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751