Vitamin D may help prevent Prediabetes progression to diabetes: Study

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-02-08T11:15:31+05:30 | Updated On 8 Feb 2021 2:42 PM IST

China: Vitamin D supplementation decreases the risk of type 2 diabetes (T2D) in people with prediabetes and significantly increases reversion of prediabetes to normoglycemia (normal blood sugar), reveals a recent review in the journal Diabetes Care. However the benefit of T2D prevention seems to be confined to only nonobese people.

Observational studies have shown low vitamin D levels to be associated with diabetes. However, it is not clear if intervention with vitamin D supplements can lower T2D risk. To determine the same, Yu Zhang, West China Hospital, Sichuan University, Chengdu, Sichuan, China, and colleagues aimed to assess whether vitamin D supplementation reduces T2D risk in prediabetes patients.

For the purpose, the researchers searched the online databases from inception to 5 July 2019 and included RCTs that assessed vitamin D supplementation versus placebo in relation to new-onset T2D in people with prediabetes. A total of eight eligible trials were identified with a total of 4,896 subjects.

Also Read: Vitamin D supplementation may help reduce high BP in elderly: Study

Key findings of the study include:

Vitamin D supplementation significantly reduced the risk of T2DM (risk ratio [RR] 0.89).
Benefit was found in nonobese subjects (RR 0.73 [95% CI 0.57–0.92]) but not in obese subjects (RR 0.95).
The reversion of prediabetes to normoglycemia occurred in 116 of 548 (21.2%) participants in the vitamin D group and 75 of 532 (14.1%) in the control group.
Vitamin D supplementation increased reversion rate of prediabetes to normoglycemia (RR 1.48).

"Individual participant data meta-analyses are needed to confirm the overall result and identify subgroups that benefit the most from supplementation," concluded the authors.

Also Read: High protein diet suppresses hunger, improves insulin sensitivity and cardiac function: Study

The study titled, "Effects of Vitamin D Supplementation on Prevention of Type 2 Diabetes in Patients With Prediabetes: A Systematic Review and Meta-analysis," is published in the journal Diabetes Care.

DOI: https://care.diabetesjournals.org/content/43/7/1650

Diabetes Caretype 2 diabetesvitamin Dprediabetesblood sugar

Source : Diabetes Care

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751