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Almonds have potential to prevent prediabetes: Study
Almonds have an effect on glucose and lipid metabolism and may be used to help prevent prediabetes.
Mumbai, India: Almonds have been shown to have an effect on glucose and lipid metabolism and may be used as a part of the food-based strategy to help prevent prediabetes especially in the young, according to a recent study which was published on the open science platform, Frontiers in Nutrition.
Over the past few decades, diabetes has become established as a major global health concern. A large percentage of the Indian population has diabetes or is at risk of pre-diabetes. Consumption of unhealthy snacks made from refined foods has increased in recent times and has resulted in a compromised state of health among the population. This has influenced metabolic health and increased the risk for the development of obesity as well as obesity associated non-communicable diseases (NCDs). One of the possible ways to improve metabolic health and reduce the risk of NCDs is by introducing healthy snacks. With this background, a group of researchers carried out a study to determine the effect of almond consumption on determinants of metabolic dysfunction—blood glucose, lipids, insulin and selected inflammatory markers.
The project was a randomized controlled, open-label, parallel arm study conducted on community living adolescents and young adults (16–25 years of age) in Mumbai, India. It was conducted over a period of 90 days and the inclusion criteria were participants in the age group of 16–25 years of age, with impaired fasting glucose levels between 100 and 125 mg/dL (5.6–6.9 mmol/L) and 2-h post-glucose value 140–199 mg/dL (7.8–11.0 mmol/L) and/or fasting hyperinsulinemia (≥15 mIU/ml) or glucose challenge hyperinsulinemia (≥80 m IU/ml). Baseline assessment was done for fasting blood glucose, fasting insulin, stimulated (2-h post 75 g glucose administration) blood glucose, stimulated insulin, glycosylated hemoglobin (HbA1c), lipid profile, oxidized LDL, adiponectin, leptin, inflammatory markers -IL-6 and TNF-α among the 275 participants. This was followed by randomisation to assign the individuals either to the almonds group or the control group. Participants in the almonds group received 56 g of raw almonds daily which was distributed in 2 packets that were to be consumed as snacks in a day. Participants in the control group received commonly consumed isocaloric (as provided by 56 g of raw almonds) Indian savory snacks of 2 varieties to prevent taste fatigue.
The mean glycosylated hemoglobin levels (HbA1c) levels showed a significant reduction in the almond group in comparison to the control group. There was also a significant reduction in the total cholesterol and LDL-c levels in the almond group in comparison to the control group, along with a decrease in the inflammatory marker, IL-6.
Overall, the study almonds were shown to have an effect on glucose metabolism by reducing HbA1c levels in just 12 weeks of consumption and manage dyslipidemia by reducing LDL-c and total cholesterol in the same population.
"Almonds can be a good healthy snack that can replace regular snacks and can be considered as a part of the food-based strategy to help prevent prediabetes especially in the young," the researchers concluded.
Reference:
The study titled, "Effect of Almond Consumption on Metabolic Risk Factors—Glucose Metabolism, Hyperinsulinemia, Selected Markers of Inflammation: A Randomized Controlled Trial in Adolescents and Young Adults," is published in the journal Frontiers in Nutrition.
DOI: https://www.frontiersin.org/articles/10.3389/fnut.2021.668622/full
Medical Dialogues Bureau consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751