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Herpes Simplex Virus laryngitis may present with stridor in kids, finds study

Written By : MD Bureau |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-01-24T20:45:36+05:30  |  Updated On 25 Jan 2021 2:02 PM IST
Herpes Simplex Virus laryngitis may present with stridor in kids, finds study
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Infection with herpes simplex virus (HSV) typically causes limited oral and genital symptoms, however, HSV can also affect the larynx and result in severe aerodigestive symptoms.

In a recent study, researchers have found that Herpes simplex virus (HSV) laryngitis manifests differently in adult vs pediatric patients because of differences in laryngeal anatomy. They also reported that HSV laryngitis is associated with significant morbidity including multi-week hospital stay and risk for needing tracheostomy in both adults and pediatric population. The research has been published in the International Journal of Pediatric Otorhinolaryngology on December 24, 2020.

Herpes simplex virus (HSV) infection of the larynx is an exceedingly rare clinical entity. It has been reported in a pediatric population who present with acute upper respiratory obstruction requiring intensive care and ventilatory support. Due to the rarity of HSV laryngitis, the symptoms and clinical course are not well understood. Therefore, researchers of Boston conducted a study to completely characterize HSV laryngitis in order to aid clinicians in understanding and recognition of HSV laryngitis.

Researchers conducted a Systematic Reviews to identify articles relating to HSV laryngitis from MEDLINE, EMBASE, and Cochrane Database. They extracted patient demographics, presenting signs and symptoms, treatment and clinical course from the selected manuscripts. They included 31 studies on HSV laryngitis that identified 36 patients (17 pediatric, 19 adults).

Key findings of the study were:

• Among the pediatric population, they noted that stridor was more common at presentation when compared with the adult population.

• They also noted that adults were more commonly presented with dysphagia and dysphonia.

• They found that adult patients were more likely to undergo tracheotomy than pediatric patients.

• The mean length of hospital stay was 21 days for children and 16 for adults respectively.

The authors concluded, "HSV laryngitis has a unique presentation in pediatrics and adults, but is nonspecific in both populations leading to delays in diagnosis and treatment. HSV laryngitis is associated with significant morbidity including multi-week hospital stay and risk for needing tracheostomy in both adults and pediatric population which demonstrates the need for clinical awareness of this complication of HSV infection".

For further information:

DOI: https://doi.org/10.1016/j.ijporl.2020.110596

Herpes simplexHSVLaryngitisInternational Journal of Pediatric OtorhinolaryngologyAdults vs children
Article Source :  International Journal of Pediatric Otorhinolaryngology 
MD Bureau
MD Bureau

    Medical Dialogues Bureau consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers.  Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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