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Probiotics improve total salivary antioxidant level, physical properties of saliva: Study
Role of oxidative stress in pathophysiology of various diseases has already been established. Antioxidants act as free radical scavenger and prevent damage to cell, at the same time affects the metabolism of several pathogenic microbes.
With increasing incidence of antibiotic resistance, alternative therapeutic treatment options are coming into picture. WHO claims probiotics to be the next most important immune defence system following antibiotic resistance.
Probiotics are effective in increasing antioxidant level thereby minimizing cellular damage and hence can be used for prevention of several diseases, finds a study conducted at the Department of Conservative Dentistry and Endodontics, AB Shetty Memorial institute of Dental Sciences, Nitte, India, published recently in the Journal of Otolaryngology –ENT Research.
Saliva being an alternative diagnostic tool poses several advantages over plasma. Its availability, easy collection, possibility of repeated non-invasive sampling, simpler technique and faster interpretation makes it ideal for screening, diagnosing and monitoring various diseases.
Very few studies have been performed on understanding the pathophysiology of oxidative stress in saliva and the potential role of probiotics on salivary antioxidant level have never been evaluated. Also the effect of probiotics on salivary buffering capacity and pH is not well understood. Mithra N Hegde and colleague Mrinalini tried to unveil the antioxidant property of probiotics in saliva along with its effect on salivary pH and buffering capacity.
The authors used unstimulated saliva from 10 individuals. The samples were analysed for total antioxidant level, pH and buffering capacity using spectrophotometer, pH paper and buffering strips respectively, before and after probiotic intake for 2 weeks.
It was found that probiotic intake led to increase in total salivary antioxidant level with no significant changes in pH and buffering capacity. Results obtained were statistically analysed using "paired t-test".
Hence, it was concluded that "probiotics are effective in increasing antioxidant level thereby minimizing cellular damage and hence can be used for prevention of several diseases. Also increase in antioxidant level can be easily assessed in saliva, thus, saliva can be used as a routine diagnostic tool."
Hegde MN, Mrinalini. Effect of probiotics on total salivary antioxidant level and physical properties of saliva: An ex-vivo study. J Otolaryngol ENT Res.2021;13(2):13?16. DOI: 10.15406/joentr.2021.13.00483
BDS, MDS( Pedodontics and Preventive Dentistry)
Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751