Asthma and allergic rhinitis may trigger onset of inflammatory bowel disease

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-12-17T17:00:46+05:30 | Updated On 17 Dec 2022 5:01 PM IST

A recent study by Namarik Alenezy and peers paned out to determine whether asthma or allergic rhinitis (AR) increased the risk of inflammatory bowel disease (IBD) diagnosis and found that all aeroallergens are plausible culprits in triggering IBD onset. The details of this study was published in the Inflammatory Bowel Diseases Journal.

This retrospective study used the administrative data of Manitoba Health and the population-based University of Manitoba IBD Epidemiology Database. They also included the numbers of prescriptions for asthma drugs and Allergic Rhinitis drugs used to identify the respective diagnosis. The study also calculated the relative risks (RRs) to assess incidence of IBD when compared with matched controls following asthma and AR diagnoses. The hazard ratios were assessed to determine asthma and AR incidence after IBD diagnosis.

They key findings of this study;

When compared with controls, ones with asthma or AR diagnoses preceding a diagnosis of IBD had increased cases with a similar outcome by IBD subtypes (Crohn's disease vs ulcerative colitis).
On the sensitivity analysis, asthma or AR diagnoses were comparable while considering at least 5, 10, 15 or 20 drug prescriptions.
Persons with IBD were more likely to develop asthma or AR than controls after being diagnosed with IBD initially.

According to the Authors in conclusion, this study demonstrates that a preexisting diagnosis of asthma or allergic rhinitis is closely associated with an significant increase in the risk of developing IBD subsequently. The findings also reinforce the importance of considering that gastrointestinal complaints in patients with asthma and allergic rhinitis that may possibly reflect a diagnosis of IBD. It also raises the notion that aeroallergens can possibly be the environmental cause(s) of IBD.

For further insight:

Alenezy, N., Nugent, Z., Herman, S., Zaborniak, K., Ramsey, C. D., & Bernstein, C. N. (2022). Aeroallergen-related Diseases Predate the Diagnosis of Inflammatory Bowel Disease. In Inflammatory Bowel Diseases. Oxford University Press (OUP). https://doi.org/10.1093/ibd/izac184

inflammatory bowel diseasesasthmaallergic rhinitis

Source : Inflammatory Bowel Diseases

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751