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Medical Bulletin 8/ November /2021

Published On 2021-11-09T11:53:08+05:30  |  Updated On 2021-11-09T15:37:43+05:30
Medical Bulletin 8/ November /2021

Overview

Here are Top Medical Stories of the day

Tralokinumab, corticosteroids helpful in AD

Atopic dermatitis (AD), is a common chronic or recurrent inflammatory skin disease and affects 15-20% of children and 1-3% of adults worldwide. Cyclosporine A (CSA) is a popularly used in AD, but treatment with CSA has potentially serious adverse effects. A phase 3 trial Capsinoids plus topical corticosteroids (TCS) as needed provided early and sustained improvements in AD signs and symptoms.

A randomized trial by J. Gutermuth and team revealed that tralokinumab 300 mg plus topical corticosteroids as needed was effective and well tolerated in patients with severe AD not adequately controlled with oral corticosteroids or who had contraindications to them.

For more details, check out the full story on the link below:

Tralokinumab Plus Topical Corticosteroids Effective In Severe Atopic Dermatitis

Smoking cessation reduces CVD risk

 A population study by Su-Min Jeong and the team revealed that smoking cessation, but not reduction, reduces the risk of cardiovascular disease (CVD). Also, a sustained cessation of smoking reduced stroke and mortality chances. The findings of the study are published in the European Heart Journal.

According to the Centers for Disease Control and Prevention (CDC), smoking cigarettes increases the risk of cardiovascular diseases (CVD), stroke, respiratory problems, etc. Tobacco use is the most common preventable cause of death however reduction doesn't help its risk factors. Su-Min Jeong and the team, therefore, aimed to assess the association of smoking cessation and reduction with the risk of cardiovascular disease.

For more details, check out the full story on the link below:

Smoking Cessation, Not Reduction Reduces Risk Of Cardiovascular Disease: Study


Peri-implantitis can cause implant removal

Peri-implantitis is the leading cause for dental implant removal (IR), according to a study published in the Journal of Periodontology

A cross-sectional study was designed to shed light on the clinical sequelae and patient satisfaction after dental implant removal (IR).

For more details, check out the full story on the link below:

Peri-Implantitis Leading Cause For Implant Removal Finds Study


DPN causes cognitive decline 

A recent study has highlighted the association between diabetic peripheral neuropathy (DPN) with lower cognitive performance in people with type 2 diabetes (T2D) of f <10 years of known duration. DPN was found to be inversely and significantly associated with measures of immediate recall and processing speed. The study was published in the Journal of Diabetes and its Complications on 15 September 2021.

There is a lack of studies examining measures of cognition are related to DPN presence and/or cardiovascular autonomic neuropathy (CAN). Also, data regarding actors potentially explaining such associations are lacking. To fill this knowledge gap, Joshua I. Barzilay, Emory University School of Medicine, Atlanta, GA, USA, and colleagues recruited participants from the Glycemia Reduction Approaches in Diabetes Study (GRADE) that examined 5047 middle-aged people with type 2 diabetes of <10 years of known duration.

For more details, check out the full story on the link below:

Diabetic Peripheral Neuropathy Associated With Cognitive Decline In Type 2 Diabetes Patients: Study


Pain, sleep quality, distress interlinked

Chronic musculoskeletal pain, sleep quality, and mental distress are strongly linked, suggests a recent study published in the Journal of sleep research.

Musculoskeletal pain generally affects the bones, joints, ligaments, tendons, or muscles. It may be induced due to an injury like fractures, which may result in sudden and extreme pain. The musculoskeletal pain often interferes with the usual activities, like sleep.

For more details, check out the full story on the link below:

Chronic Pain, Sleep Quality And Mental Distress Strongly Related, Suggests Study


Speakers

Dr. Nandita Mohan

BDS, MDS( Pedodontics and Preventive Dentistry)

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
tralokinumab atopic dermatitis British Journal of Dermatology cardiovascular disease smoking cessation european heart journal peri-implantitis implant removal journal of periodontology journal of diabetes and its complications diabetic peripheral neuropathy type 2 diabetes cognition actigraphy chronic musculoskeletal pain insomnia mental distress multilevel modelling journal of sleep research 
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