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  • Temperature exhibits...

Temperature exhibits U-shaped relationship with bacteremia, highest risk above 39.4 degree celsius

Written By : Aditi |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-04-10T10:15:43+05:30  |  Updated On 10 April 2023 1:18 PM IST
Temperature exhibits U-shaped relationship with bacteremia, highest risk above 39.4 degree celsius
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USA: An original research article entitled "Relationship Between Oral Temperature and Bacteremia in Hospitalized Patients" has concluded that with increase in temperature, bacteremia increases.

The study is published in the Journal of General Internal Medicine.

Recognising and managing bacteremia early is lifesaving. One of the well-known markers of bacteremia is fever. However, there needs to be more research on the predictive value of temperature.

To investigate this further, researchers described temperature as a predictor of bacteremia and other infections using a study design as a retrospective review of electronic health record data.

The study setting was a US healthcare system with 13 hospitals. The patients were adults without malignancy or immunosuppression.

The primary measure measured in the study was Maximum temperature, bacteremia, influenza and skin and soft tissue (SSTI) infections. Blood cultures and ICD-10 coding determined this.

The results of the study could be summarised as:

  • Out of 97,174 patients, nearly 1,518 constituting 1.6%, had bacteremia.
  • 1,392 patients constituting 1.4%, had influenza
  • Three thousand two hundred eighty patients constituting 3.3%, had an SSTI.
  • There was no identifiable temperature threshold providing sensitivity and specificity for bacteremia.
  • 45% of patients with bacteremia had a maximum temperature ≥ 100.4ËšF (38ËšC).
  • There was a U-shaped relationship between temperature and bacteremia.
  • The highest risk was above 103ËšF (39.4ËšC).
  • With increasing temperatures, there were positive likelihood ratios for influenza and SSTI. The threshold effect was at ≥ 101.0 ËšF (38.3ËšC).
  • For patients aged more than 65 years, the temperature effect was similar but blunted and frequently lacked fever despite bacteremia.

Concluding further, most patients with bacteremia had maximum temperatures below 100.4 ËšF. There is a more positive likelihood ratio of the fact that with high temperature, bacteremia increases.

They finally wrote efforts to predict bacteremia should incorporate temperature as a continuous variable.

Further reading:

Speaker SL, Pfoh ER, Pappas MA, Schulte R, Hu B, Gautier TN, Rothberg MB. Relationship Between Oral Temperature and Bacteremia in Hospitalized Patients. J Gen Intern Med. 2023 Mar 30. Doi: 10.1007/s11606-023-08168-6. Epub ahead of print. PMID: 36997793.

temperatureU shaped relationship39.4 degree celciusbacteremiaJournal of General Internal Medicine
Source : Journal of General Internal Medicine
Aditi
Aditi

    BDS, MDS in Periodontics and Implantology

    Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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