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  • Adult Asthma Linked to...

Adult Asthma Linked to Higher Risk of Multiple Comorbidities Over 15 Years: Study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2025-07-04T21:45:15+05:30  |  Updated On 5 July 2025 11:37 AM IST
Adult Asthma Linked to Higher Risk of Multiple Comorbidities Over 15 Years: Study
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Researchers have found in a new study over a 15-year follow-up that adults with asthma showed significantly higher rates of comorbidities, including a 10-fold increased risk of chronic obstructive pulmonary disease (COPD) and a 4-fold higher risk of conditions like acute rhinosinusitis, chronic rhinosinusitis with nasal polyps, and atopic dermatitis, compared to matched non-asthmatic individuals.

Asthma is a common chronic disease characterised by variable respiratory symptoms and airflow limitation, affecting roughly 4%–10% of the adult population. Adult asthma is associated with higher all-cause mortality compared to individuals without asthma. In this study, we investigate the comorbidities that may affect the management of asthma. Total of 1648 adults with asthma and 3310 individuals without asthma aged 30–93 were matched with age, gender and area of residency, and followed from 1 January 1997 to 31 December 2013.

Baseline information was collected with questionnaires 1997 and follow-up register data from the national discharge registry Finnish Institute for Health and Welfare. Data included diagnoses from outpatient care and day surgery of specialised health care, and data from inpatient care of specialised and primary health care. We included all main diagnoses that had at minimum 200 events and number of diagnoses based on their common appearance with adult asthma.

Results The mean follow-up time varied between 14.2 and 15.1 years, and age at the time of enrolment was 53.9 years for subjects without asthma and 54.4 years for patients with asthma. Chronic obstructive pulmonary disease was 10 times more common among asthmatics. Risk of acute rhinosinusitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis and vocal cord dysfunction was fourfold and risk of pneumonia was 2.5 times and chronic rhinosinusitis was 1.8 times more common among asthmatics. Sleep apnoea, gastro-oesophageal reflux disease, diabetes, allergic rhinitis and dysfunctional breathing were twofold and cataract nearly twofold higher in the asthmatic group. Adult asthma was also significantly associated with musculoskeletal diseases, incontinence and bronchiectasis.

The most common and most severe comorbidity of adult asthma in this study was chronic obstructive pulmonary disease. Other common comorbidities of adult asthma include acute rhinosinusitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis, allergic rhinitis, dysfunctional breathing, diabetes, pneumonia, sleep apnoea and gastro-oesophageal reflux disease.

Reference:

Riikka Emilia Lemmetyinen, Sanna Katriina Toppila-Salmi, Anna But, Risto Renkonen, Juha Pekkanen, Jari Haukka, Jussi Karjalainen - Comorbidities associated with adult asthma: a population-based matched cohort study in Finland: BMJ Open Respiratory Research 2024;11:e001959.

AdultAsthmaLinkedHigherRiskMultipleComorbiditiesOver15 YearsStudy
Source : BMJ Open Respiratory Research
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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