- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Encephalitis and cytokine storm secondary to respiratory viral infection among children: case report
Unites States: Encephalitis is a syndrome characterized by brain damage secondary to an inflammatory process that is manifested by cognitive impairment and altered cerebral spinal fluid analysis; it may evolve with seizures and coma. Despite viral infections representing the main cause of encephalitis in children, respiratory syncytial virus (RSV) and parainfluenza virus are mostly associated with respiratory presentations.
A CASE REPORT article published in Frontiers in Pediatrics discussed cytokine storm in children with a history of Encephalitis secondary to respiratory viral infection.
The lead researcher was Santos et al., with Duke University and the University of Maryland colleagues.
Respiratory syncytial virus and parainfluenza virus is mainly associated with respiratory presentations. The inflammatory phenomena from Encephalitis secondary to viral agents present an exacerbated host response called a cytokine storm.
The link between infectious agents and neurologic syndromes causing cytokine storm is rare. There needs to be more elaboration on underlying pathophysiology because it needs to be better understood.
The present case report is of a 5-year-old female and a 2-year-old male. These two children were infected with parainfluenza and respiratory syncytial virus, respectively. Nasopharyngeal PCR made the confirmation.
The children were admitted into the pediatric ICU (intensive care unit). The main reason for hospital admission was Encephalitis and multiple organ dysfunction. The manifestations recorded were seizures and hemodynamic instability.
The findings from the MRI findings revealed that:
- The first patient had bilateral hyper signal on FLAIR in the cerebral hemispheres (posterior parietal and occipital regions). During the acute phase, IL-6 was elevated and evolved with a fast recovery of the clinical presentations.
- The second patient had general systemic complications, followed by cerebral edema and death.
Finally concluding, the researchers said that.
Encephalitis, secondary to respiratory viral infection, evolves with cytokine storm and multiorgan inflammatory response in children.
Further reading:
Encephalitis and cytokine storm secondary to respiratory viruses in children: 2 case reports. Front. Pediatr. Sec. Pediatric Critical Care Volume 10 - 2022 | doi: 10.3389/fped.2022.1049724
BDS, MDS in Periodontics and Implantology
Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751