- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Intermittent Bolus Paravertebral Block Opioid-Sparing analgesic effect among patients undergoing hepatectomy
A recent study published in the BMC Surgery found potential benefits of intermittent bolus paravertebral block on analgesia and recovery in patients undergoing open hepatectomy. The study, conducted on 80 patients aged between 18 and 70 years, has shed light on the advantages of utilizing paravertebral ropivacaine in the management of postoperative pain.Hepatectomy, a surgical procedure...
A recent study published in the BMC Surgery found potential benefits of intermittent bolus paravertebral block on analgesia and recovery in patients undergoing open hepatectomy. The study, conducted on 80 patients aged between 18 and 70 years, has shed light on the advantages of utilizing paravertebral ropivacaine in the management of postoperative pain.
Hepatectomy, a surgical procedure involving the partial removal of the liver, often requires substantial postoperative pain management. To address this, researchers carried out a randomized trial, enrolling patients with American Society of Anesthesiologists (ASA) level I-III, who were scheduled for hepatectomy with a J-shaped subcostal incision. The participants were divided into two groups: one receiving intermittent bolus paravertebral ropivacaine (with 0.5% loading and 0.2% infusion) and the other receiving a 0.9% saline infusion. A total of 38 patients were included in each group, and their outcomes were closely monitored.
The primary outcome measured in the study was the cumulative intravenous morphine consumption through a patient-controlled analgesic pump during the first 48 hours after the operation. Remarkably, the results demonstrated that patients who received the paravertebral block exhibited significantly lower cumulative morphine consumption at postoperative 24 and 48 hours compared to the control group. The opioid-sparing effect of the paravertebral block offers an alternative approach to pain management, potentially reducing the risks associated with opioid use and promoting faster recovery.
Additionally, the study evaluated pain intensity using numerical rating scales at rest and during activity. The group receiving the paravertebral block reported lower pain scores at various time intervals, including postoperative 4 hours and 12 hours. These findings further reinforce the effectiveness of the paravertebral block in managing postoperative pain.
Furthermore, the benefits of the paravertebral block extended beyond the hospital stay. Three months after the surgery, patients in the paravertebral block group experienced lower rates of hypoesthesia (numbness) compared to the control group. This suggests that the use of paravertebral ropivacaine may contribute to improved long-term outcomes and patient satisfaction following hepatectomy.
Reference:
Wang, J., Cui, X., Zhang, Y., Sang, X., & Shen, L. (2023). The effects of intermittent bolus paravertebral block on analgesia and recovery in open hepatectomy: a randomized, double-blinded, controlled study. In BMC Surgery (Vol. 23, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12893-023-02125-0
Neuroscience Masters graduate
Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751