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Minimal access surgery safe and feasible alternative to conventional surgery for breast cancer: JAMA

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-10-12T19:30:00+05:30  |  Updated On 12 Oct 2022 7:30 PM IST
Minimal access surgery safe and feasible alternative to conventional surgery for breast cancer: JAMA
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Minimal access breast surgery may be a safe and feasible alternative to conventional surgery of breast cancer, according to a recent study published in the JAMA Surgery.

Minimal access breast surgery (MABS) has been used in breast cancer management. However, long-term predictive data associated with MABS vs conventional breast surgery (CBS) are lacking.

A study investigated long-term therapeutic outcomes associated with MABS vs CBS for breast cancer management.

In this single-centre retrospective cohort study, 9184 individuals were assessed for inclusion. After exclusions, 2412 adult female individuals were included who were diagnosed with stage 0 to III breast cancer, underwent unilateral breast surgery between January 2004 and December 2017, and had no distant metastasis or history of severe underlying disease. Propensity score matching was performed to minimize selection bias. Data were analyzed from January 1, 2004, to December 31, 2019. Data on demographic and tumour characteristics and long-term outcomes were collected and analyzed.

Results:

  • This study included 2412 patients
  • Of these, 603 patients underwent MABS (endoscopic, endoscopy-assisted, or robot-assisted procedures in 289, 302, and 12 patients, respectively) and 1809 patients underwent CBS.
  • The median follow-up time was 84 months
  • Intergroup differences were not significant for the following parameters: 10-year local recurrence-free survival, regional recurrence-free survival, and distant metastasis-free survival
  • The 5-, 10-, and 15-year disease-free survival rates in the MABS group were 85.9%, 72.6%, and 69.1%, respectively.
  • The corresponding rates in the CBS group were 85.0%, 76.6%, and 70.7%.
  • The intergroup differences were not significant
  • The MABS group's 5-, 10-, and 15-year overall survival rates were 92.0%, 83.7%, and 83.0%, respectively.
  • The corresponding rates in the CBS group were 93.6%, 88.7%, and 81.0%. The intergroup differences were not significant
  • Post hoc subgroup analysis showed no significant intergroup differences in disease-free survival.

In this cohort study, long-term outcomes following MABS were not significantly different from those following CBS in patients with early-stage breast cancer. MABS may be a safe and feasible alternative in this patient population.

Reference:

Wan A, Liang Y, Chen L, et al. Association of Long-term Oncologic Prognosis With Minimal Access Breast Surgery vs Conventional Breast Surgery. JAMA Surg. Published online October 05, 2022. doi:10.1001/jamasurg.2022.4711


breast surgeryJAMA Sugeryendoscopicroboticconventional breast surgery
Source : JAMA Surgery
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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