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Women have higher mortality following CABG compared to men

Written By : Aditi |Medically Reviewed By : Dr. Kamal Kant Kohli   |  
Women have higher mortality following CABG compared to men
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New York: An original investigation published in JAMA Surgery has concluded that women are at higher risk of experiencing adverse outcomes after coronary artery bypass grafting (CABG).

Researchers from the Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York and the Department of Cardiac Surgery, Medical University of Vienna, in their cohort study of more than 1 million patients, reported this finding. They reported no significant improvement over the last decade.

Previous studies have reported that women undergoing CABG have higher mortality and morbidity than men. There is a lack of data mentioning if this difference has decreased over the last decade. The researchers evaluated the trend related to outcomes from 2011 to 2020 (US). Nearly 1 297 204 patients underwent surgery during this period.

The study summary includes the following points:

  • Operative mortality was the primary outcome.
  • The composite of operative mortality and morbidity were the secondary outcomes.
  • The researchers calculated the association of the female sex with CABG.
  • The mean age of patients was 66.0 years, including 24.5 % of women.
  • The unadjusted operative mortality was higher in women at 2.8%.
  • The women had a higher overall unadjusted incidence of the composite of operative mortality and morbidity than men, with 22.9%.
  • The attributable risk for operative mortality varied for females from 1.28 in 2011 to 1.41 in 2020. The change was insignificant over the study period.
  • The attributable risk was 1.08 in 2011 and 2020 for the composite of operative mortality and morbidity. The change was insignificant over the study period.

Concluding further, women have a greater risk of adverse outcomes after CABG and the researchers did not report any significant improvement over the last decade.

Further investigations are warranted regarding determinants of operative outcomes in women.

Further reading:

Gaudino M, Chadow D, Rahouma M, et al. Operative Outcomes of Women Undergoing Coronary Artery Bypass Surgery in the US, 2011 to 2020. JAMA Surg. Published online March 01, 2023. doi:10.1001/jamasurg.2022.8156

womenmenCABGCoronary artery bypass graftingJAMA SurgerymortalityMorbiditymorbidity and mortality outcomesoperative mortality and morbidity
Source : JAMA Surgery
Aditi
Aditi

    BDS, MDS in Periodontics and Implantology

    Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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