High doses of VX-548 reduced acute pain over a period of 48 hours after major surgery: NEJM Jacinthlyn Sylvia5 Aug 2023 9:15 AM ISTA recent study has found effective acute pain management with VX-548, an oral, highly selective inhibitor targeting the NaV1.8 voltage-gated sodium...
COVID-19 not linked to development of type 1 diabetes in children: NEJM Dr. Kamal Kant Kohli3 Aug 2023 10:30 AM ISTUSA: COVID-19 infection didn't appear to precipitate a diagnosis of type 1 diabetes in children according to a prospective, multinational cohort...
Pitavastatin effective in treating cardiovascular diseases in HIV patients Niveditha Subramani1 Aug 2023 11:30 AM ISTHuman immunodeficiency virus (HIV) infection is a greater threat and a gateway to a wide range of diseases. The risk of cardiovascular disease is...
Maternal vaccine promising for prevention of Group B Streptococcus infection in infants: NEJM Dr. Kamal Kant Kohli24 July 2023 8:00 PM ISTUSA: A recent study published in The New England Journal of Medicine has revealed the potential of a maternally administered vaccine for infant group...
Investigational RNA interference therapeutic agent Zilebesiran effective for treatment of hypertension Niveditha Subramani22 July 2023 11:45 AM ISTAngiotensinogen has previously been assumed to be a passive substrate, however recent studies reveal an inherent conformational mechanism that is...
MIND diet not superior to standard diet for preventing cognitive decline among older adults Dr. Kamal Kant Kohli19 July 2023 8:00 PM ISTUSA: A phase III MIND trial has shed light on the relevance of the MIND Diet, a hybrid of the DASH (Dietary Approaches to Stop Hypertension) and...
Dersimelagon, an effective oral treatment for patients with erythropoietic protoporphyria: Phase 2 trial Medha Baranwal8 July 2023 9:45 AM ISTUSA: A phase 2 study published in The New England Journal of Medicine claimed that oral dersimelagon may be a safe and effective treatment option for...
Vorasidenib shows promising results in IDH1- or IDH2-Mutant low-grade gliomas: NEJM Dr.Niharika Harsha B7 July 2023 8:00 PM ISTNew research revealed that Vorasidenib, an oral brain-penetrant inhibitor of mutant IDH1 and IDH2 enzymes significantly improves progression-free...
Pegozafermin, a potential treatment for improving fibrosis in NASH patients: Phase 2b Trial Dr. Kamal Kant Kohli5 July 2023 8:00 PM ISTUSA: The positive outcomes of a phase 2b trial support the further advancement of pegozafermin into phase 3 trials for NASH treatment. If successful,...
Use of high-dose hemodiafiltration improves survival in individuals with kidney failure: NEJM Chumbeni4 July 2023 10:30 AM ISTNetherlands: Researchers have found in the multinational, randomized, controlled trial involving 1360 kidney failure patients that high-dose...
Transcatheter repair safe and effective among patients with mitral regurgitation secondary to cardiomyopathy: NEJM Aditi3 July 2023 11:00 AM ISTPatients receiving transcatheter repair of mitral regurgitation secondary to cardiomyopathy have good safety outcomes compared to medical therapy...
Nivolumab plus chemotherapy improves survival in Stage III Non-Small-Cell Lung Cancer: NEJM Chumbeni30 Jun 2023 8:00 PM ISTSpain: A recent study published in The New England Journal of Medicine has revealed that combining Nivolumab and Chemotherapy treatment in patients...
