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Vitamin D insufficiency associated with Urinary Tract Symptoms: Study
A recent study suggests a significant association between Vitamin D insufficiency and increased risk of urinary tract symptoms. The study details were published in The Journal of Urology on 18 November 2020.
Several studies have demonstrated that vitamin D deficiency was associated with an increased incidence of infectious disease, including urinary tract diseases. However, the influence of Vitamin D deficiency and its association with urinary tract infections (UTI) remains controversial. Cumulative studies have shown that vitamin D may be associated with lower urinary tract symptoms, but the findings have been inconsistent. For this purpose, the researchers conducted a study to systematically evaluate the relationship between vitamin D and lower urinary tract symptoms.
They conducted a meta-analysis from the database of PubMed, Scopus and Embase of articles up to June 2020 and analyzed a total of 23 studies including 86332 participants meeting inclusion criteria to evaluate the relationship between vitamin D and lower urinary tract symptoms. They conducted a qualitative analysis to examine heterogeneity and the robustness of the results.
After the systemic review and analysis researchers have found, Vitamin D insufficiency was associated with a 1.37- to 2.06-fold increased likelihood of having lower urinary tract symptoms, and patients with lower urinary tract symptoms had significantly lower levels of vitamin D. They also found Vitamin D intake was significantly associated with an 11% reduction in the risk of lower urinary tract symptoms. They observed Vitamin D supplementation was associated with a pooled decrease in odds of lower urinary tract symptoms of 0.89 in five cohort studies and significant reductions in urinary incontinence episodes in four randomized controlled trials. In a subgroup analysis of non Asians, females, and patients with urinary incontinence, they found an impact relationship between vitamin D deficiency and symptoms, both concerning deficiency and the potential benefits of supplementation.
The authors concluded, Consistent results indicated that vitamin D insufficiency was a crucial risk factor for lower urinary tract symptoms and that vitamin D supplementation showed promising effects on these symptoms. It would be of great guiding significance to consider vitamin D status when treating lower urinary tract symptoms.
For further information:
https://www.auajournals.org/doi/10.1097/JU.0000000000001441
Medical Dialogues Bureau consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751