Daily use of lozenge containing arginine and probiotics may benefit children with dental caries
Daily use of lozenge containing arginine and probiotics may benefit children with dental caries suggests a new study published in the Journal of Dentistry.
Results
The study was completed by 288 children. The dropout rate was 15%. The increase in ∆mean dICDAS3–6msf-s and ∆mean d/DICDAS3–6m/M-s/S-f/F-s/S was lower in the intervention group (p = 0.007). No differences were found for gingivitis- and plaque occurrence. No product-related side effects were reported. This study followed ICH-GCP including external monitoring.
Daily consumption of a lozenge containing prebiotic arginine and two strains of probiotics showed safe use and statistically significantly reduction in caries incrementbut no effect on the mean plaque or gingivitis occurrence in children. The use of a lozenge with arginine and probiotics combined has a promising potential as a supplementary tool for future management of caries.
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