Maternal folic acid supplementation may delay dental development of children: Study
Written By : Dr. Shravani Dali
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2021-12-13 16:30 GMT | Update On 2021-12-13 16:37 GMT
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Maternal folic acid supplementation delays the dental development of children, according to a recent study published in the Community Dentistry and Oral Epidemiology
Low folic acid, folate and vitamin B12 might affect tooth formation and mineralization. The conversion of folic acid into folate is catalysed by the methylenetetrahydrofolate (MTHFR) enzyme which is encoded by the MTHFR gene. Among 3728 mothers and their 10-year-old children from the Generation R Study, a group of researchers investigated associations of maternal folic acid supplementation and prenatal folate and vitamin B12 concentrations with child dental development. Secondly, we checked the modifying effect of MTHFR-C677T polymorphism.
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