Combo of spironolactone and minoxidil effective against androgenetic alopecia in both genders: Study
Egypt: Both a 5% topical solution of minoxidil and a 5% topical solution of spironolactone, might be safe to use in a twice-daily dosage for the treatment of androgenetic alopecia (AGA) in both men and women, states a study in the Journal of Cosmetic Dermatology.
Mohamed L. Elsaie, Medical and Clinical Research Institute, National Research Centre, Egypt, and associated further found that combining both medications in a single topical dose form can increase efficacy and give greater advantages.
Androgenetic alopecia (AGA) is a common chronic illness of dermatology that causes hair fall in both men and women. Dr. Elsaie and the team conducted the study with the objective of dermoscopically assessing and comparing the impact of a combination of topical spironolactone solution (5%) and topical minoxidil solution (5%) in treating AGA in both sexes.
The study included one hundred and twenty patients with a diagnosis of androgenetic alopecia. They were divided into three groups; each group comprised 40 patients. Patients in Group A were treated with 5% topical minoxidil solution, those in Group B were treated with 5% topical spironolactone solution, and Group C patients were treated with a combination of 5% topical spironolactone and minoxidil.
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