Healthy lifestyle tied to reduced risk of PAD in genetically susceptible type 2 diabetes patients: Study
China: A recent study has shown a lower risk of peripheral artery disease (PAD) among individuals with type 2 diabetes (T2D) with a favourable lifestyle, independent of genetic predisposition to PAD. The findings were published online in Diabetes Care on January 5, 2024.
The research from the UK Biobank, spanning over 13.5 years, revealed that adhering to a favourable lifestyle characterized by regular exercise, non-smoking, moderate alcohol intake, a high-quality diet, sufficient sleep, and optimal waist-to-hip ratio led to a remarkable reduction in the risk of peripheral artery disease in T2D patients. A favourable lifestyle also partly mitigated the genetic risk of PAD.
The study was conducted by Gang Liu, Huazhong University of Science and Technology, Wuhan, China, and colleagues to evaluate the association between modifiable lifestyle factors and peripheral artery disease among individuals with type 2 diabetes.
The researchers included 14,543 individuals with type 2 diabetes from the UK Biobank. A weighted healthy lifestyle score was defined using adequate sleep duration, optimal waist-to-hip ratio, moderate alcohol consumption, regular physical activity, high-quality diet and nonsmoking. They were categorized into unfavourable, intermediate, and favourable lifestyles.
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