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  • Scientists develop new...

Scientists develop new one-step cheaper test for breast cancer

Hina ZahidWritten by Hina Zahid Published On 2020-08-08T10:06:38+05:30  |  Updated On 8 Aug 2020 10:10 AM GMT
Scientists develop new one-step cheaper test for breast cancer

Scientists have created a rapid and affordable test for breast cancer that is designed for use in developing regions, where patients often face delayed diagnoses that worsen their outcomes. The diagnostic showed an initial accuracy of 100% when tested in a small group of 68 patients, and could yield repeated results in less than 1 hour. Although more testing with large patient groups...

Scientists have created a rapid and affordable test for breast cancer that is designed for use in developing regions, where patients often face delayed diagnoses that worsen their outcomes.

The diagnostic showed an initial accuracy of 100% when tested in a small group of 68 patients, and could yield repeated results in less than 1 hour. Although more testing with large patient groups is necessary, the technique's speed and ease-of-use could help clinicians in resource-limited settings overcome barriers to rapid cancer diagnosis.

Spotting cancers early on is challenging enough in developed countries, but it can be even more difficult in low- and middle-income countries, where more than two thirds of deaths from cancer occur. Due to the lack of medical infrastructure and healthcare specialists, diagnoses can be delayed for months and often come only after a patient has developed advanced disease. To address the need for new cancer tests, Jouha Min and colleagues harnessed image cytometry, a technique that images and analyzes individual cells for malignancy.
They developed a compact and automated cytometry test named CytoPAN that studies breast cells gathered with fine-needle aspiration, a less invasive alternative to standard biopsies. In a validation study in South Korea, CytoPAN could be applied to 63 of 68 patients with breast cancer and spotted cancers with an accuracy of 100%, using as few as 50 cells per specimen. The test also spotted ER/PR and HER2, key cancer biomarkers, with an accuracy of 93% and 96%, respectively. The method offers several features for usability and affordability: it yields results quickly, integrates a simplified workflow that requires minimal training, and uses test kits with an estimated cost of only $5, more than five times cheaper than current diagnostics. The authors say future trials should test CytoPAN with a wider range of biomarkers and in other regions such as sub-Saharan Africa, where women with breast cancer face additional risks such as HIV infection.
http://dx.doi.org/10.1126/scitranslmed.aaz9746


cancer testing breast cancer cytopan science translational medicine 
Source : Science Translational Medicine
Hina Zahid
Hina Zahid

    Hina Zahid Joined Medical Dialogue in 2017 with a passion to work as a Reporter. She coordinates with various national and international journals and association and covers all the stories related to Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in the medical field. Email: editorial@medicaldialogues.in. Contact no. 011-43720751

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