Lilly diabetes drug slashes deaths in patients with heart risk
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Eli Lilly and Co's new Jardiance pill slashed deaths by 32 percent in patients with type 2 diabetes at risk of heart attack and stroke, a finding that could make it a mainstay diabetes treatment and triple its use, according to researchers and analysts.
Lilly shares jumped as much as 9 percent after data from the trial was released Thursday at a medical meeting in Stockholm.
"This is the first diabetes therapy to show robust effect in reducing cardiovascular death. It really is big news," said Dr. Bernard Zinman, director of the Diabetes Centre at Mount Sinai Hospital in Toronto, who led the three-year study of 7,000 people.
Because about one-half of the deaths in people with type 2 diabetes are caused by cardiovascular disease, reducing cardiovascular risk is considered essential to diabetes care. Type 2 diabetes is the most common form of the disease and is linked to obesity.
Jardiance, a once-a-day pill which won U.S. approval last year, belongs to a new family of treatments called SGLT2 inhibitors that include Johnson & Johnson's Invokana and AstraZeneca Plc's Farxiga. They lower blood sugar by inhibiting reabsorption of glucose in the kidneys.
Lilly shares jumped as much as 9 percent after data from the trial was released Thursday at a medical meeting in Stockholm.
"This is the first diabetes therapy to show robust effect in reducing cardiovascular death. It really is big news," said Dr. Bernard Zinman, director of the Diabetes Centre at Mount Sinai Hospital in Toronto, who led the three-year study of 7,000 people.
Because about one-half of the deaths in people with type 2 diabetes are caused by cardiovascular disease, reducing cardiovascular risk is considered essential to diabetes care. Type 2 diabetes is the most common form of the disease and is linked to obesity.
Jardiance, a once-a-day pill which won U.S. approval last year, belongs to a new family of treatments called SGLT2 inhibitors that include Johnson & Johnson's Invokana and AstraZeneca Plc's Farxiga. They lower blood sugar by inhibiting reabsorption of glucose in the kidneys.
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