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  • High prevalence of...

High prevalence of angina with no obstructive CAD observed in females, reveals coronary angiography study

Dr.Niharika Harsha BWritten by Dr.Niharika Harsha B Published On 2022-11-01T20:00:49+05:30  |  Updated On 2022-11-01T20:01:18+05:30
High prevalence of angina with no obstructive CAD observed in females, reveals coronary angiography study

A new investigation found that there was a high prevalence of Angina with no obstructive coronary artery disease (ANOCA) in patients undergoing invasive coronary angiography. Angina with no obstructive coronary artery disease (ANOCA) was stable and was mostly seen in female patients. The study was published in the Canadian Journal of Cardiology. Angina with no obstructive coronary...

A new investigation found that there was a high prevalence of Angina with no obstructive coronary artery disease (ANOCA) in patients undergoing invasive coronary angiography. Angina with no obstructive coronary artery disease (ANOCA) was stable and was mostly seen in female patients.

The study was published in the Canadian Journal of Cardiology. 

Angina with no obstructive coronary artery disease is a common and under-recognized clinical entity. It's not clear whether the referral patterns for diagnosing chest pain have changed. Hence, researchers conducted a retrospective, population-based cohort study to determine if the prevalence of patients diagnosed with ANOCA with coronary angiography has modified over time. 

Also Read: The piano chord that cures nightmares

 Between 1995 and 2020 Alberta patients who had their first coronary angiogram for a chest pain syndrome were extracted from the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) database. A temporal trend analysis was performed to compare patients with ANOCA to obstructive coronary artery disease (CAD), and the predictors of ANOCA were investigated. 

Results: 

  • 121,066 patients were included, out of which 26% had ANOCA with a mean age of 62 years. There were 31% females in the study.
  • The percent of ANOCA to obstructive CAD ranged between 24.2% and 26.7% in all patients (p<0.001), 19.4% and 21.4% in patients with acute coronary syndromes (p=0.002), and 30.6% and 37.5% in patients with stable angina (p<0.001).
  • Female sex, younger age, history of atrial fibrillation, and stable angina (versus myocardial infarction; versus unstable angina) were independent predictors of ANOCA. 
Also Read: Brain stroke cases increasing in the younger population
  • Traditional cardiovascular risk factors were associated with obstructive CAD. 

This study allows excluding obstructive CAD with less invasive testing, especially in females. 

Further reading: Patel S, Fung M, Liang Z, Butalia S, Anderson TJ. Temporal trends of the prevalence of angina with no obstructive coronary artery disease (ANOCA) [published online ahead of print, 2022 Oct 20]. Can J Cardiol. 2022;S0828-282X(22)00977-1. doi: 10.1016/j.cjca.2022.10.018 

Angina coronary artery disease Angina with no obstructive coronary artery disease ANOCA coronary angiography obstructive CAD atrial fibrillation stable angina cardiovascular risk factors 
Source : Canadian Journal of Cardiology
Dr.Niharika Harsha B
Dr.Niharika Harsha B

    BDS, MDS

    Dr.Niharika Harsha B (BDS,MDS) completed her BDS from Govt Dental College, Hyderabad and MDS from Dr.NTR University of health sciences(Now Kaloji Rao University). She has 4 years of private dental practice and worked for 2 years as Consultant Oral Radiologist at a Dental Imaging Centre in Hyderabad. She worked as Research Assistant and scientific writer in the development of Oral Anti cancer screening device with her seniors. She has a deep intriguing wish in writing highly engaging, captivating and informative medical content for a wider audience. She can be contacted at editorial@medicaldialogues.in.

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