- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Novel rectal expulsion device as good as current gold standard for functional constipation: Study
USA: Results from a recent proof-of-concept study showed that a novel device called rectal expulsion device (RED) yields similar results and tolerability to balloon expulsion test (BET) -- the current gold standard in clinical practice. RED is a novel, investigational, point-of-care, single-use disposable device that helps to identify constipated patients with an evacuation disorder. The study appears in the journal Clinical Gastroenterology and Hepatology.
Functional constipation (FC) is one of the most commonly encountered gastrointestinal conditions in practice. Practice guidelines universally recommend that patients having typical constipation symptoms and no alarm feature be treated empirically with laxative therapy and dietary/lifestyle interventions. However, these treatments frequently have already been tried, when a patient reaches a gastroenterologist. The next best step in management guidelines in this all-too-common scenario is anorectal function testing (anorectal manometry [ARM] and BET) because treatment can then be targeted toward pelvic floor dysfunction or colon transit abnormalities.
However, owing to some observations such as more than 95% of patients continue to take only over-the-counter laxatives and receive empirical dietary advice, fewer than 2% undergo a physiologic evaluation to ascertain the cause of their symptoms. Indeed, more than 90% of patients desire more effective treatment options. This calls into question the misguided "one size fits all" empirical treatment strategy.
Against the above background, William D. Chey, Division of Gastroenterology and Hepatology, Michigan Medicine, Ann Arbor, Michigan, and colleagues aimed to compare RED to a currently available balloon device to measure BET and found a similar proportion of constipated patients with a positive test (it was not stated whether the patients were positive to both tests).
"Patients with functional constipation had similar results in the ability to expel the RED and the balloon expulsion test," wrote the authors. "Patient ratings on device smoothness, shape, size, overall comfort, and procedural duration were comparable between the two devices."
To conclude, RED delivers a strong value proposition to potentially disrupt the paradigm in evaluating/managing chronic constipation as an easy-to-use, point-of-care device to rapidly screen for an evacuation disorder and immediately triage the 98% of patients with laxative-refractory chronic constipation who never undergo anorectal function testing to appropriate therapy in community practice.
Reference:
Chey WD, Baker JR, Watts L, Harris A, Shah ED. Development of a Simple, Point-of-Care Device to Test Anorectal Function in Patients with Constipation: Randomized Clinical Trial. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 2021 Dec. DOI: 10.1016/j.cgh.2021.11.034. PMID: 34864156.
MSc. Biotechnology
Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at  editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751