Even Normal fasting blood sugar significantly linked to Frozen shoulder: Study
High blood sugar or Hyperglycemia is the most commonly cited risk factor for frozen shoulder. However, no study has established whether fasting blood sugar levels within the normoglycemic range are associated with idiopathic adhesive capsulitis (IAC) or frozen shoulder.
Dr Hyung BinPark along with his panel of researchers have reported a significant association of fasting blood sugar levels within normal range with development of frozen shoulder.
The study has been recently published in the Journal of Shoulder and Elbow Surgery.
This study hypothesized that increments of fasting blood sugar levels within the normoglycemic range would be linked to frozen shoulder. This study investigated any association between normoglycemic fasting blood sugar levels and frozen shoulder.
Adhesive capsulitis ,commonly known as frozen shoulder occurs when ligaments around the shoulder joint swell and become stiff. Previous research has shown that people with poorly controlled diabetic patients are up to twice prone to suffer from frozen shoulder.
The current study investigated the association between normoglycemic fasting blood sugar levels and IAC, if any. The study design was a case control one comprising of a group of 151 patients with IAC without other risk factors whereas the control subjects had normal shoulder function. Both the groups had a non contributory past medical history. The sample was divided into 4 categories i.e. <85, 85-89, 90-94, and 95-99 mg/dL depending on the fasting glucose levels. Researchers further assessed multiple co-variables like body mass index, serum lipid profiles, thyroid hormone levels, fasting blood sugar levels, glycosylated hemoglobin A1c, and high-sensitivity C-reactive protein.
Findings of the study brought forth the following facts.
- Fasting glucose levels in the 90-94 mg/dL quartile (which are currently considered normoglycemic) or higher were significantly positively associated with IAC (P ≤ .034).
- Higher cholesterol levels and high-sensitivity C-reactive protein were significantly associated with IAC (P ≤ .030).
- A negative relation was noted between patients with fasting glucose levels below 85 mg/dL and IAC.
Though many studies have associated IAC with hyperglycemia,this study is the first to analyse the relation of frozen shoulder in a normoglycemic population.
The significantly high positive correlation of frozen shoulder in people within normal blood sugar levels points out that other risk factors need to be further evaluated in future studies, the researchers opined.
Read the full article on: https://doi.org/10.1016/j.jse.2020.03.017