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Eisai-Biogen Alzheimer's drug Lecanemab should be priced below Aduhelm: Report

Ruchika SharmaWritten by Ruchika Sharma Published On 2022-12-25T14:00:41+05:30  |  Updated On 25 Dec 2022 2:00 PM IST
Eisai-Biogen Alzheimers drug Lecanemab should be priced below Aduhelm: Report
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Treatment with the drug may provide a small or even substantial benefit to patients with early Alzheimer's, but there remains a possibility of net harm due to brain-swelling side effects, according to ICER.

Bengaluru: An influential drug pricing research group said Eisai Co Ltd and Biogen Inc's new Alzheimer's disease treatment lecanemab should be priced lower than the drug Aduhelm that was developed by the companies.

In a draft report released on Thursday, the Institute for Clinical and Economic Review (ICER) said a price range of between $8,500 and $20,600 annually for lecanemab would meet some commonly used thresholds for cost effectiveness.
"Biogen halved the price of its first Alzheimer's drug Aduhelm last year to $28,200 for a person with average weight, amid tepid sales and reimbursement hurdles. Treatment with lecanemab for patients with Alzheimer's appears to be "promising but inconclusive," ICER said.
ICER is not a government agency and has no authority to set prices, but many large health insurers take their reports into account when they negotiate prices. Eisai and Biogen did not immediately respond to requests for comment on the ICER report.
The characterization by ICER is "less than glowing", but lecanemab beats out other available options for treatment of Alzheimer's, Wells Fargo analyst Mohit Bansal said. Eisai in November said lecanemab reduced the rate of cognitive decline on a clinical dementia scale by 27 percent, compared with a placebo. It also gave new details on side effects, including brain swelling and brain bleeding.
Read also:
Bristol-Myers, Eisai in up to USD 3.1 billion deal to develop cancer drug candidate
Treatment with the drug may provide a small or even substantial benefit to patients with early Alzheimer's, but there remains a possibility of net harm due to brain-swelling side effects, according to ICER.
Shares of Eisai fell on Friday after a report of a third death in a trial of lecanemab. The company confirmed the death to Reuters and said it was investigating the cause.

Read also: Merck, Eisai get Japanese nod for cancer cocktail drug Keytruda, Lenvima

EisaiBiogenAlzheimer's diseaselecanemabAduhelmInstitute for Clinical and Economic Review
Source : Reuters
Ruchika Sharma
Ruchika Sharma

    Ruchika Sharma joined Medical Dialogue as an Correspondent for the Business Section in 2019. She covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She has completed her B.Com from Delhi University and then pursued postgraduation in M.Com. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751

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